Childhood Astrocytomas Treatment (PDQ®): Treatment - Health Professional Information [NCI]-Changes t

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Childhood Astrocytomas Treatment (PDQ®): Treatment - Health Professional Information [NCI]-Changes to this Summary (06 / 20 / 2014) The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

This summary was reformatted.

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General Information About Childhood Astrocytomas

Added text to state that one retrospective study of 53 children with gangliogliomas demonstrated BRAF V600E staining in approximately 40% of tumors. Five-year recurrence-free survival was worse in the V600E-mutated tumors (about 60%) than in the tumors that did not stain for V600E (about 80%) (cited Dahiya et al. as reference 34).

This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.

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